Yamato GB210A Versatile Mini Spray Dryer
The Yamato GB210A mini spray dryer is a compact and versatile spray dryer that can easily produce powder on a laboratory scale. The GB-210A spray dryer unit is capable of drying ultra small samples as low as 30ml of sample and can spray dry it into fine powder 1μm to 25μm in size. Moreover, our versatile GB210A compact spray dryer can perform a variety of applications from preliminary experiments in a pilot plant to drying work in general laboratories.
True to providing convenience and efficiency to our users, the GB210A spray dryer model employs a one-touch removal system that makes removal and cleaning of the drying chamber, cyclone, and product container much easier.
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Spray dryer GB210A and GAS410 solvent recovery system in preclinical drug product manufacturing
Application: Formation of enabled formulations to support preclinical development
The user needed a closed loop spray dryer to allow for spraying of organic solvent based solutions. The spray dryer needed to support small scale pilot batches for initial characterization and larger scale production to support in vivo studies.
User Insights:
Why Customers Choose Yamato?
“We invested in the GB210A and GAS410 to support preclinical development of our lead pharmaceutical candidates. The simplicity, robustness, and cost all contributed to our decision to purchase this spray dryer setup. In addition, the option to perform fluid bed drying on the same equipment is great to have for future formulation research.”
“We have used a technique to spray directly into small vials and jars, increasing the yield,
especially for small scale batches”
Why does this user recommend Yamato spray dryers?
“Product support has been especially great. The team is very responsive and flexible in trying to help their customers.”
GB210A
Features
- Samples unstable at high temperatures can be reliably processed into fine powder. Heat is applied instantly and indirectly to the powder itself
- Prepared fine powder will not be oxidized in the spray dryer, contains minimal moisture and is contaminant-free
- Direct drying from solution/suspension liquid to fine powder with a reduced risk of contamination
- No pre or post processes such as filtration, separation, or pulverization are required
- Processing of samples containing organic solvents is made possible by connecting the Organic Solvent Recovery Unit GAS410 to the spray dryer
- Spray dryer unit can also be used as a fluid bed drying granulator by installing a separate mini bed attachment GF200 instead of GF300 spray drying attachment
- An automatic lift is equipped as standard to enable easy installation or removal of glass drying chamber attachment
- A service outlet (max. 2A) and a sample stand are equipped as standard for connecting a magnetic mixer for stirring suspended liquid sample
- Stable spray drying using a unique peristaltic pump, nozzle cooling mechanism, pulse jet mechanism and a nozzle knocker enable stable spray drying
Can your sample/solution be spray dried successfully?
Here’s a quick reference for sample types and the parameters used to successfully spray dry them. These are real, verified samples used in labs today.
Spray Dryers
Spray drying equipment has improved over the years. Today, you can process products from milk powder to antibiotics using spray dryers. Yamato’s spray dryer models are suitable for experimental and R&D purposes. You can use our spray dryers for drying, fine powdering, powder mixing, agglomerating, encapsulating, and englobing.
Commercial Food Products
Spray dryers were used widely during the Second World War to produce milk powder. Hence, it is no surprise that the largest market for lab spray dryers nowadays is in the food industry particularly in powdered milk and instant coffee production.
From milk production, the use of spray drying technology has extended to the production of powdered varieties of coffee, algae, gum arabic, protein hydrolysates, yeast extract, starches, and non-dairy creamers to name a few.
You can now rapidly create agglomerates or powder from liquids such as emulsions, suspensions, and solutions since spray dryers are fully-automated and continuous. Moreover, spray drying equipment such as the ADL311SA—a Compact & Economical Spray Dryer by Yamato—are highly suitable for drying both heat-resistant and heat-sensitive foods, allowing shorter residence time with no oxidation and minimal moisture remaining.
Spray drying is also used for encapsulating active substances, homogenizing these into slurries or emulsions before drying. By encapsulating food products, you get to protect your product from heat degradation and therefore improve final product functionality.
Pharmaceutical Products
Not all medical dosages are soluble. Hence, spray drying technology affords the pharmaceutical industry an economical and fast alternative to converting liquid feed into powdered medications and additives such as extracts, infusions, inorganic medicinal salts, vitamin C, and adrenaline.
Since the 1940s, the use of spray drying equipment in pharmaceuticals has advanced from simple drying methods to sophisticated processes such as the production of excipients like ointment bases and preservatives and the isolation of active ingredients that are either hard-to-crystallize or heat-sensitive.
Needless to say, spray drying is an ideal process for those requiring precise attributes especially in the morphology, stability, and particle size of your pharmaceutical products.
In just a single continuous process, you get to convert liquid feedstock into a well-defined powder and get desired properties including precise residual solvent, moisture level, particle morphology, as well as density and size of particulates, which is crucial in the pharmaceutical industry. With high-performance spray dryers like the Yamato DL410 Large Capacity Spray Dryer, you can produce fine particles with sizes from 10 to 100 micrometers, which are considered by many to be difficult to achieve.
Furthermore, you are guaranteed a contaminant free powder with minimal moisture and zero oxidation, so you can guarantee patrons that your products are safe.
Industrial Products
Aside from food and pharmaceutical production, spray dryers are essential for the industrial creation of powdered materials such as catalyst supports, ceramic materials, microalgae, detergents, and paint pigments.
Used, basically, for encapsulation by most industries, applications of spray drying equipment in an industrial setting includes the production of not just powders but also textiles, adhesives, pesticides, carbonless copy paper, and anti-corrosive coatings just to mention a few. The microencapsulation technique involves the use of coatings such as polyvinyl alcohol, sodium alginate, starch, and gelatin.
By encapsulating, you get to reap numerous benefits; one is an extended shelf life for your product and another is increased stability. On the other hand, you also get to decrease the evaporation of the volatile core in products such as paints and pesticides. Aside from those, you also get to reduce oxygenation, prevent a chemical reaction, and improve handling properties of adhesives.
Now, if you are spraying acidic samples for either aqueous or organic solvent, before exhausting to environment or recirculating to the GAS410 Solvent Recovery Unit, we recommend using the GWS410 Organic Solvent Washing Unit to neutralize the air or gas which contains acidic ingredients.